研制了中药穴位经皮给药系统——止咳平喘膜剂。采用双室渗 透扩散装置考察膜剂的经皮吸收性能; 测定膜剂于小鼠膻中、肺腧等穴位用药后的穴位电阻 值、Na+-K+-ATP酶活性和经皮吸收量。结果表明，膜剂中有效成分之一的黄芩甙以零 级速率透过皮肤,渗透性能良好;穴位给药后皮肤电阻值降低，酶活性升高，经皮吸收量增加 ,与非穴位给药相比有显著性差异。 Developed Chinese medicine point transdermal delivery system - cough and asthma film. The transdermal absorbability of the film was investigated by dual-chamber osmotic diffusion device. The acupoint resistance value, Na + -K + -ATPase activity and transdermal absorbance were measured after the film was applied to the skin of mice, The results showed that baicalin, one of the effective components in the film, permeated the skin at a zero rate and had good permeability. After the acupoint administration, the skin resistance decreased, the enzyme activity increased, the percutaneous absorption increased, and the non-acupoint administration Compared to significant differences.