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肺炎支原体( MP)是引发社区获得性肺炎的一种常见的致病微生物，多见于儿童和青少年，其与哮喘的发生、急性恶化发作及慢性症状难以控制密切相关。但是，至今支原体感染诱发哮喘的机制尚不明确，可能与MP的直接损伤作用、免疫球蛋白E介导的免疫反应、细胞因子和炎性介质的释放及宿主体质有关。此外，支原体感染引发的哮喘也有自身的特点。总之，两者密切相关，及时检测支原体，预测疗效，调整用药方案非常必要。“,”Mycoplasma pneumoniae( MP) is a common causative organism of community-acquired pneu-monia in children and young adults,which also has a close relationship with the development,acute exacerba-tion and persistence of chronic difficult-to-control symptom of asthma. However,the mechanisms inducing or causing asthma remain unclear. Possible mechanisms include direct damage of bronchial mucosa,IgE-media-ted immune response,a variety of cytokines,the release of inflammatory mediators and the propensity of host. In addition,asthma caused by infection of MP has its own characteristics. In a word,the occurrence of asthma is closely related to MP infection,therefore it′s necessary to test the mycoplasma,predict the efficacy,and adjust the medication plan.