间皮瘤是一种少见的肿瘤,好发部位为胸膜、腹膜、心包、心肌内膜及睾丸鞘膜。于1870年Wagner首先描述了1例胸膜间皮瘤。Klemper和Rabio氏于1931年报道了间皮瘤,而且并命名为结节性淋巴腺瘤。至1942年由Stont和Murrag氏通过组织学培养证实了组织学的间皮瘤起源,在50年代报道了间皮瘤为恶性肿瘤,接着在南非地区也有所报道,在那里发现了间皮瘤,同时还从病因学上提出了和石棉接触有关的看法。40年代前很少有人将此病 Mesothelioma is a rare tumor with pleural, peritoneal, pericardial, myocardium, and testicular sheaths. In 1870, Wagner first described a case of pleural mesothelioma. Klemper and Rabio reported mesothelioma in 1931 and they were named nodular lymphomas. By 1942, the histological origin of mesothelioma was confirmed by histological culture by Stont and Murrag. In the 1950s, mesothelioma was reported as a malignant tumor. It was also reported in South Africa, where mesothelioma was found. At the same time, it also put forward the views related to asbestos exposure from the etiology. Few people had this disease before the 1940s