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目的 :探讨肝癌患者血清转化生长因子α检测的意义。方法 :采用放射免疫分析法检测 42例肝癌患者和 2 5例肝硬化患者血清中 TGF-α的水平 ,并与 AFP进行比较分析。结果 :对照组 TGF-α为 13.2 4± 4.10 ng/ L ,肝硬化组为 12 .10± 3.1ng/ L,与对照组无明显差异 ,P>0 .0 5 ;肝癌组为 18.85± 9.6 1ng/ L,明显高于对照组和肝硬化组 ,P<0 .0 1。结论 :TGF- α能配合 AFP检测肝癌 ,可作为肝癌诊断的一项检测指标。
Objective: To investigate the significance of serum transforming growth factor-α in patients with liver cancer. Methods: The levels of TGF-α in serum of 42 patients with hepatocellular carcinoma and 25 patients with cirrhosis were detected by radioimmunoassay and compared with AFP. Results: In the control group, TGF-α was 13.2 4 ± 4.10 ng / L and cirrhosis was 12.10 ± 3.1 ng / L, which was not significantly different from that of the control group (P> 0.05). The liver cancer group was 18.85 ± 9.6 1 ng / L, significantly higher than the control group and cirrhosis group, P <0. Conclusion: TGF-α can be used in combination with AFP to detect liver cancer, which can be used as a diagnostic indicator of liver cancer.