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在宫颈癌发生过程中,人乳头瘤病毒(human papillomavirus,HPV)感染是必要的环境因素,而宿主遗传易感性则影响感染结局。单核苷酸多态性(SNPs)是新一代的遗传学标记,可用于寻找肿瘤相关基因。本文就宫颈癌相关基因单核苷酸多态性的研究进展做一综述。
In the process of cervical cancer, human papillomavirus (HPV) infection is an essential environmental factor, while host genetic susceptibility affects the outcome of infection. Single nucleotide polymorphisms (SNPs) are a new generation of genetic markers that can be used to find tumor-associated genes. This article reviews the progress of single nucleotide polymorphisms of cervical cancer related genes.