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目的:探讨胸腔镜肺叶切除术在早期肺癌治疗中的临床应用。方法:选取我院收治的肺癌患者142例,分为两组,每组71例,对照组予常规开胸肺叶切除术,实验组予胸腔镜肺叶切除术,均采用全身麻醉,双腔气管插管。手术后,观察比较两组患者的临床疗效,手术情况及恢复情况,疼痛评分以及手术前、术后第1天和第5天的血清CRP情况。结果:1手术后,两组患者的临床疗效均有所改善,实验组明显优于对照组,差异有统计学意义(P<0.05)。2手术后,两组患者的手术情况及恢复情况相比较,实验组明显优于对照组,差异有统计学意义(P<0.05)。3手术后,两组患者的血清CRP术后第1天与术前相比较均有所升高,第5天的血清CRP都有所降低,实验组与对照组相比较,差异有统计学意义(P<0.05)。结论:胸腔镜肺叶切除术治疗早期肺癌能够改善患者血清CRP水平,提高临床疗效,安全可行。
Objective: To investigate the clinical application of thoracoscopic lobectomy in the treatment of early stage lung cancer. Methods: 142 cases of lung cancer admitted to our hospital were divided into two groups (n = 71 in each group). The control group was given routine thoracotomy and lobectomy. The experimental group was treated by thoracoscopic lobectomy. All patients underwent general anesthesia, tube. After the operation, the clinical efficacy, operation and recovery, pain score and the serum CRP level on the first day and the fifth day after operation were observed and compared between the two groups. Results: After operation, the clinical curative effect of both groups improved, the experimental group was obviously better than the control group, the difference was statistically significant (P <0.05). After operation, the operation and recovery of two groups of patients were significantly better than the control group, the difference was statistically significant (P <0.05). 3 After surgery, the serum CRP levels of both groups increased on the first day after operation compared with that before operation, and the serum CRP decreased on the fifth day. The difference between the experimental group and the control group was statistically significant (P <0.05). Conclusions: Thoracoscopic lobectomy for early lung cancer can improve serum CRP level and improve clinical efficacy, which is safe and feasible.