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目的探讨多发性硬化(MS)的临床特点。方法综合分析27例多发性硬化患者的一般临床资料、病变部位、重要辅助检查及治疗转归。结果MS多见于青年女性,起病多为急性或亚急性,病程多呈缓解复发,多数无明显诱因,脊髓、视神经受累多见,电生理、影像学检查有助于诊断,糖皮质激素治疗有效。结论根据临床特点,综合神经电生理、脑脊液检查及影像学检查能大大提高临床确诊率,其中诱发电位、磁共振成像意义较大。
Objective To investigate the clinical features of multiple sclerosis (MS). Methods A total of 27 cases of multiple sclerosis patients clinical data, lesions, important auxiliary examination and treatment outcome. Results MS more common in young women, mostly acute or subacute onset, most of the course of remission and relapse, the majority of no obvious incentive, spinal cord, optic nerve involvement more common, electrophysiology, imaging studies can help diagnose, glucocorticoid treatment effective . Conclusion According to clinical features, comprehensive neuroelectrophysiology, cerebrospinal fluid examination and imaging examination can greatly improve the clinical diagnosis rate, including evoked potentials, magnetic resonance imaging greater significance.