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目的探讨改良B-Lynch缝合联合欣母沛治疗顽固性宫缩乏力产后出血的临床疗效。方法选取重庆市武隆区妇幼保健院2015年12月—2017年1月收治的顽固性宫缩乏力产后出血患者80例,随机分为对照组与治疗组,各40例。对照组患者予以改良B-Lynch缝合联合缩宫素治疗,治疗组患者予以改良B-Lynch缝合联合欣母沛治疗。比较两组患者临床疗效、止血时间、术中出血量、术中输血量、术后24 h出血量,观察患者不良反应及子宫切除发生情况。结果治疗组患者治疗总有效率高于对照组(P<0.05)。治疗组患者止血时间短于对照组,术中出血量、术中输血量、术后24 h出血总量少于对照组(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。两组患者均未切除子宫。结论改良B-Lynch缝合联合欣母沛治疗顽固性宫缩乏力产后出血的临床疗效确切,可快速止血,减少出血量和输血量,且安全性高。
Objective To investigate the clinical efficacy of modified B-Lynch suture combined with Xinmaopei in the treatment of refractory uterine inertia postpartum hemorrhage. Methods 80 cases of refractory uterine inertia postpartum hemorrhage admitted in Wulong District Maternal and Child Health Hospital of Chongqing from December 2015 to January 2017 were randomly divided into control group and treatment group, 40 cases each. Patients in the control group were treated with modified B-Lynch suture combined with oxytocin, and patients in the treatment group were treated with modified B-Lynch suture combined with Xinmaopei. The clinical curative effect, bleeding time, intraoperative blood loss, intraoperative blood transfusion, blood loss at 24 hours after operation were compared between two groups. The adverse reaction and hysterectomy were observed. Results The total effective rate of treatment group was higher than that of control group (P <0.05). The bleeding time in the treatment group was shorter than that in the control group. The blood loss during operation, blood transfusion during operation and total bleeding at 24 h after operation were lower than those in the control group (P <0.05). Two groups of patients with adverse reactions, the difference was not statistically significant (P> 0.05). The two groups of patients did not remove the uterus. Conclusion The improved B-Lynch suture combined with Xin Maopei treatment of intractable uterine inertia postpartum hemorrhage, the exact clinical curative effect, can quickly stop bleeding, reduce blood loss and blood transfusion, and high safety.