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目的调查吉林地区非妊娠妇女B族链球菌(GBS)带菌情况,探讨其与妇科有关情况的关系。方法对本地区2096例妇女常规妇科体检,取生殖道分泌物进行GBS培养、鉴定和药敏试验。结果吉林地区GBS带菌率为18.3%。36~45岁组妇女带菌率较高,有自然流产史者较无自然流产者带菌率高。使用宫内节育器避孕者GBS带菌率较不用此法避孕者阳性率略高,但无统计学差异。有阴道炎症、宫颈炎症与附件炎症表现的患者GBS阳性率较高,尤以阴道与宫颈炎者表现明显,具有统计学差异。抗生素敏感试验结果表明,分离培养的GBS菌株对青霉素和头孢菌素类药物基本敏感。结论吉林地区非妊娠妇女GBS带菌率尚在健康人群带菌率的范围内,菌株对青霉素类药物和头孢菌素类药物基本敏感,但也应加强检测。
Objective To investigate the carriage of Streptococcus group B Streptococcus (GBS) in non-pregnant women in Jilin Province and to explore its relationship with gynecological conditions. Methods 2096 women in the region routine gynecological examination, reproductive tract secretions GBS culture, identification and drug sensitivity test. Results The rate of GBS in Jilin was 18.3%. 36-45 year-old women with higher rates of women with spontaneous abortion than those without spontaneous abortion with high rates. The use of intrauterine contraceptives GBS carrier rate of contraception than those who do not have a slightly higher positive rate of contraception, but no significant difference. Vaginal inflammation, inflammation of the cervix and annex inflammation in patients with high GBS positive rate, especially in vaginal and cervicitis were significantly, with statistical differences. The results of antibiotic susceptibility test showed that isolates of GBS were basically sensitive to penicillin and cephalosporin. Conclusion The prevalence of GBS in non-pregnant women in Jilin area is still within the range of healthy population. The strains are sensitive to penicillins and cephalosporins, but should be strengthened.