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近年来随着医疗技术的发展,恶性肿瘤的诊断及治疗有了较大的进步,但其发病率亦逐渐升高。正常情况下人体免疫系统可以有效地维持抵抗外来病原入侵、监视自身变异细胞及避免自身过度免疫反应的平衡状态,而肿瘤的发生、发展与肿瘤逃避免疫系统的攻击和机体抗肿瘤的免疫效应低下密切相关。抗原刺激后,初始CD4+T细胞活化、扩增,分化发育
In recent years, with the development of medical technology, there has been a great improvement in the diagnosis and treatment of malignant tumors, but the incidence has also been gradually increasing. Under normal circumstances, the human immune system can effectively maintain resistance against invading foreign pathogens, monitor their own variant cells and prevent their own immune response over the balance of the state, and the occurrence and development of tumors and tumor escape immune system attacks and the body’s anti-tumor immune effect is low closely related. After antigen stimulation, the initial CD4 + T cell activation, expansion, differentiation and development