目的了解急性脑梗死患者脑微出血(CMB)的发生率,分析其危险因素。方法选择2008年3月-2012年3月住院的急性脑梗死患者122例,行MRI磁敏感加权成像,根据有无CMB分为两组,对其一般临床资料和临床生化指标进行比较,探讨急性脑梗死合并CMB的相关危险因素;根据CMB的程度分为三组,分析颈动脉内膜增厚与CMB程度之间的关系。结果CMB组血清HDL水平显著性高于非CMB组(P<0.05),LDL水平显著性低于非CMB组(P<0.05)。年龄、高血压、脑卒中史、吸烟史在CMB组中的比例显著性高于非CMB组,差异有统计学意义(P<0.05)。CMB患者颈动IMT异常率显著性高于无CMB组(χ2=7.05,P<0.05),并且在轻、中、重三组中IMT异常率也具有显著差异(χ2=8.83,P=0.02)。结论在急性脑梗死患者中,CMB发生与年龄、高血压、脑卒中史、吸烟史、颈动脉内膜增厚、血清HDL及LDL水平相关。 Objective To understand the incidence of cerebral micro-hemorrhage (CMB) in patients with acute cerebral infarction and analyze its risk factors. Methods A total of 122 acute cerebral infarction patients hospitalized from March 2008 to March 2012 were selected. MRI magnetic resonance weighted imaging was performed. According to the presence or absence of CMB, the clinical data and clinical biochemical parameters were compared. The acute According to the degree of CMB, the patients were divided into three groups to analyze the relationship between carotid intima-media thickness and the degree of CMB. Results Serum HDL level in CMB group was significantly higher than that in non-CMB group (P <0.05), and LDL level was lower in CMB group than in non-CMB group (P <0.05). The proportions of age, hypertension, history of stroke and smoking history in CMB group were significantly higher than those in non-CMB group (P <0.05). The abnormal IMT rate in CMB patients was significantly higher than that in patients without CMB (χ2 = 7.05, P <0.05), and there was also a significant difference in IMT abnormalities among the three groups (χ2 = 8.83, P = 0.02) . Conclusions In patients with acute cerebral infarction, CMB occurs with age, hypertension, history of stroke, smoking history, carotid intimal thickening, serum HDL and LDL levels.