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目的:调查肿瘤患者疲劳状况并探讨其影响因素。方法:应用疲劳症状量表及一般状况登记表,对300例肿瘤相关性疲劳患者进行面对面问卷式调查,收集人口统计学特征、肿瘤及治疗相关信息、疲劳程度、持续时间及对生活质量影响等临床资料,采用SPSS13.0软件统计分析其影响因素。结果:性别、化疗次数、放疗、生物靶向治疗、内分泌治疗、白细胞减少和血小板减少对疲劳的影响无统计学意义,P>0.05;年龄、肿瘤分期、唑来膦酸对疲劳持续时间的影响有统计学意义,P<0.05;贫血对疲劳程度和生活质量的影响差异有统计学意义,P<0.05;正在化疗、肿瘤进展患者及有无规律体育锻炼对疲劳程度、对生活质量和疲劳持续时间的影响差异均有统计学意义,P<0.05。结论:肿瘤进展及正在化疗患者疲劳程度重,持续时间长,对生活影响明显。肿瘤分期、化疗、高龄、贫血和有无规律体育锻炼及特殊药物治疗均为肿瘤相关性疲劳的影响因素。
Objective: To investigate the fatigue status of cancer patients and to explore the influencing factors. Methods: A total of 300 patients with cancer-related fatigue were surveyed by face-to-face questionnaire and the demographic characteristics, tumor and treatment-related information, degree of fatigue, duration and quality of life were collected using the Fatigue Symptom Inventory and General Status Register Clinical data, using SPSS13.0 software statistical analysis of its influencing factors. Results: The effects of gender, chemotherapy, radiotherapy, bio-targeted therapy, endocrine therapy, leucopenia and thrombocytopenia on fatigue were not statistically significant (P> 0.05); age, tumor stage and the effect of zoledronic acid on fatigue duration There was statistical significance, P <0.05; anemia on the degree of fatigue and quality of life were significantly different, P <0.05; in patients with chemotherapy, tumor progression and regular physical exercise on the degree of fatigue, quality of life and fatigue continued The differences in time were statistically significant, P <0.05. Conclusion: Tumor progression and patients undergoing chemotherapy have severe fatigue, long duration and significant impact on life. Tumor staging, chemotherapy, advanced age, anemia and regular physical exercise and special drug treatment are all the factors that affect tumor-related fatigue.