改进了邻溴苯基－２－唑啉的合成方法，使得Ｎ－（β－羟乙基）－２－溴苯甲酰胺在氯化亚砜作用下缩合成唑啉的收率从４０％左右提高到８４％，并避免了使用ＮａＨ试剂，为芳基－２－唑啉的合成提供一条方便、经济的路线．实验结果表明，反应温度对唑啉的收率的影响显著，随着反应温度的升高收率明显降低，室温下几乎得不到目标产物．根据实验结果推测其反应过程是经过互变异构酰亚胺中间物Ⅰ进行的 The method for synthesizing o-bromophenyl-2-oxazoline has been improved so that the yield of N- (β-hydroxyethyl) -2-bromobenzamide condensed into oxazoline under the action of thionyl chloride is from 40 % To about 84%, and avoids the use of NaH reagents, providing a convenient and economical route to the synthesis of aryl-2-oxazoline. The experimental results show that the reaction temperature has a significant effect on the yield of oxazoline. With the increase of the reaction temperature, the yield is obviously decreased, and the target product is scarcely obtained at room temperature. According to the experimental results speculated that the reaction process is through the tautomeric imide intermediate Ⅰ