氟桂嗪治疗４６例小儿偏头痛的疗效及血小板聚集性的观察，采用比浊法测定血小板聚集性。治疗前，患儿组的血小板聚集性高于正常对照组（Ｐ＜０．０１），治疗后有明显下降，临床症状亦好转，从头痛发作次数和程度看，有效率为８２．６１％。细胞内游离钙的水平和血小板聚集与血管收缩有密切关系。氟桂嗪通过阻滞钙离子内流，降低血小板聚集性，抑制血管痉挛，可能是治疗本病的主要作用途径。 Treatment of 46 children with flunarizine migraine efficacy and platelet aggregation observed by turbidimetric platelet aggregation. Before treatment, platelet aggregation in children group was higher than that in normal control group (P <0.01). After treatment, the platelet aggregation was significantly decreased and clinical symptoms improved. The effective rate was 82.61% from the number and degree of headache attacks. Intracellular free calcium levels and platelet aggregation and vasoconstriction are closely related. Flunarizine by blocking the influx of calcium, reduce platelet aggregation, inhibition of vasospasm, may be the treatment of the main pathways of this disease.