论文部分内容阅读
目的探讨直流电复律对持续性心房颤动(房颤)患者B型脑钠肽(BNP)水平的影响及临床意义。方法 49例持续性房颤患者(房颤组),分别检测其入院时、电复律后24h血浆BNP水平,同时选择47例窦性心律患者作为对照组,并检测其入院时的血浆BNP水平。结果房颤组和对照组入院时血浆BNP的水平分别为(349.6±102.5)pg/ml和(218.1±74.2)pg/ml,两组间有统计学差异(P<0.05)。房颤组电复律后24h血浆BNP水平低于电复律前[(251.1±64.8)pg/ml vs.(349.6±102.5)pg/ml](P<0.05)。结论 BNP不仅是反映早期心功能受损的敏感指标,而且和心律失常相关,检测血浆BNP水平有助于评估房颤患者的预后。
Objective To investigate the effect and clinical significance of DC cardioversion on B-type natriuretic peptide (BNP) in patients with persistent atrial fibrillation (AF). Methods 49 patients with persistent atrial fibrillation (AF) were enrolled in this study. Plasma BNP levels were measured at admission and 24 h after electrical cardioversion. At the same time, 47 patients with sinus rhythm were selected as control group and plasma BNP levels . Results Plasma BNP levels at admission were (349.6 ± 102.5) pg / ml and (218.1 ± 74.2) pg / ml, respectively, with significant differences between the two groups (P <0.05). The level of plasma BNP was lower at 24 hours after cardioversion than that before electrical cardioversion [(251.1 ± 64.8) pg / ml vs. (349.6 ± 102.5) pg / ml] (P <0.05). Conclusion BNP is not only a sensitive indicator of early impaired cardiac function, but also associated with arrhythmia. Detecting plasma BNP levels may be helpful to evaluate the prognosis of patients with atrial fibrillation.