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目的 为探讨白塞病侵及大血管病人的发病情况、临床特征 ,并提出预防和治疗措施。方法 回顾性分析我院 1983～ 1999年住院治疗的 2 1例白塞病侵及大血管病人的临床情况及转归。结果 白塞病的大血管病变发生率为 15 .4% ,其中动脉受累占 19% ,静脉受累占 71.4% ,动静脉均受累占 9.6 %。病程平均为 5 .2年 ,男∶女 =2 0∶ 1。结论 白塞病的大血管病变常发生于病情重及反复发作的男性患者 ,累及的部位广泛 ,容易误诊。积极应用激素和免疫抑制剂控制白塞病病情活动 ,并适时抗凝及外科手术治疗是防治白塞病的大血管病变及改善预后的有效方法
Objective To investigate the incidence of Behcet’s disease and macrovascular disease, clinical features, and proposing preventive and therapeutic measures. Methods The clinical data and prognosis of 21 cases of Behcet’s invasion and macrovascular disease hospitalized from 1983 to 1999 in our hospital were retrospectively analyzed. Results The incidence of macrovascular disease in Behcet’s disease was 15.4%, of which arterial involvement accounted for 19%, venous involvement 71.4% and arteriovenous involvement 9.6%. The average course of disease was 5.2 years, male: female = 20: 1. Conclusions Behçet’s disease often occurs in male patients with severe and recurrent major macrovascular diseases. It involves a wide range of parts and is easily misdiagnosed. Active application of hormones and immunosuppressive agents to control Behcet’s disease activity, and timely anticoagulation and surgical treatment of Behcet’s disease is to prevent large vessel disease and improve prognosis, an effective method