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对厌氧菌有效的抗菌药物如氯霉素、林可霉素、氯林可霉素,都有潜在的严重毒性。磺胺对厌氧菌也有抗菌作用,但对其疗效尚无肯定的临床评价。过去关于灭滴灵治疗厌氧菌感染的报道,大多系用于腹腔内感染且仅为口服,本文报告静滴和口服灭滴灵治疗厌氧菌引起的严重败血症。厌氧菌败血症患者多伴有生殖道、胃肠道病变或气性坏疽。静滴时取等渗0.5%W/V的缓冲水溶液,每100毫升含灭滴灵500毫克,每8小时一次,每次持续滴注20分钟,依据临床情况酌情改用口服,疗程一般为10天。50例中男21
Anaerobic bacteria effective antibacterial drugs such as chloramphenicol, lincomycin, clindamycin, are potentially serious toxicity. Sulfonamides also have an antibacterial effect on anaerobic bacteria, but there is no definite clinical evaluation of their efficacy. In the past about metronidazole treatment of anaerobic infections are mostly used for intraperitoneal infection and only for oral use, this article reports intravenous and oral metronidazole treatment of severe sepsis caused by anaerobic bacteria. Anaerobic sepsis patients often accompanied by genital tract, gastrointestinal lesions or gas gangrene. When taking intravenous infusion of isotonic 0.5% W / V aqueous solution, every 100 ml containing metronidazole 500 mg, once every 8 hours, each infusion continued for 20 minutes, depending on clinical circumstances, as appropriate, switch to oral, treatment is generally 10 day. 50 cases of male 21