论文部分内容阅读
目的 :观察热退灵中药擦浴剂对内毒素所致发热家兔模型以及 2 ,4 -硝基苯酚所致发热大鼠模型的影响 ,并与酒精擦浴、小柴胡汤冲剂及氨基比林进行对比研究。方法 :用热退灵擦浴剂对家兔、大鼠模型进行解热、对大鼠、小鼠模型的抗炎和对小鼠疼痛模型进行镇痛实验研究。结果 :热退灵中药擦浴剂比酒精擦浴退热维持时间长 (P <0 0 5) ;比小柴胡冲剂退热起效快、效果好 (P <0 0 1 ) ;比复方氨基比林注射效果好 (P <0 0 1 ) ;中药擦浴剂对大鼠有良好的抗炎作用 (P <0 0 1 ) ;对小鼠醋酸扭体反应及热刺激所致疼痛反应有良好的镇痛作用 (P <0 0 1 )。结论 :热退灵擦浴剂的解热、抗炎和镇痛作用均优于各对照组
OBJECTIVE: To observe the effects of heat-reducing Chinese herbal bathing agent on febrile rat models induced by endotoxin and febrile rat models induced by 2, 4-nitrophenol, and to compare alcohol rubbing bath, Xiaochaihu Tang granules and aminopyrine Conduct comparative studies. METHODS: Antipyretic effects of rabbits and rat models were studied by thermal retreating wipe bath, and anti-inflammatory effects on rat and mouse models and analgesic experiments on mouse pain models were studied. RESULTS: The heat-releasing Chinese herbal wiping agent had a longer duration of heat retention than the alcohol-based wiping bath (P < 0.05); it had faster onset of fever and better results than Xiaochaihu granules (P <0 01); Lin injection effect was good (P <0 01); Chinese Herbal Rubbing Agent had good anti-inflammatory effect on rats (P <0 01); it had good response to acetic acid writhing reaction and pain caused by thermal stimulation in mice. Analgesic effect (P < 0 01). Conclusion : The antipyretic, anti-inflammatory and analgesic effects of hot-back-lin bathing agent were better than that of the control group.