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目的研究绝经妇女绝经年限与性激素、血脂及血液流变学各项指标之间的关系。方法随机选择绝经期妇女125例 ,根据绝经年限的长短 ,分组如下 :A组(1~5年 ) ,30例 ,年龄(48.5±3 .1)岁 ,B组 (6~10年 ) ,37例 ,年龄(58 .5±4 .1)岁 ,C组 (11~15年 ) ,38例 ,年龄(65 .2±3 .7)岁 ,D组 (16~20年 ) ,10例 ,年龄(68±4 .7)岁 ,E组 (>20年 ) ,10例 ,年龄(70 .8±3 .6)岁。测定各组妇女血脂、内分泌激素及血液流变学指标。结果(1)随着绝经年限的增加 ,女性血脂有升高的趋势。(2)绝经妇女雌激素水平随绝经年限的增加而逐渐降低 ,促黄体生成素和促卵泡生成素则呈先逐渐升高然后逐渐降低。(3)绝经妇女大多数血液流变学指标处于异常状态 ,其中血浆粘度随绝经年限的增加有升高的趋势 ,血沉和K值等指标的变化则表现为先下降 ,然后逐步升高。结论妇女绝经年限的长短决定了绝经妇女性激素、血脂水平和血液流变学指标的异常程度 ,绝经年限越长 ,上述指标的异常程度越显著
Objective To study the relationship between menopausal women’s years of menopause and sex hormones, blood lipids and blood rheology indicators. Methods A total of 125 cases of menopausal women were randomly divided into the following groups according to their menopause duration: Group A (1-5 years), 30 cases (48.5 ± 3.1) years old, Group B (6-10 years), 37 (58.5 +/- 4.1 years), C (11-15 years), 38 cases (65.2 ± 3.77 years), D (16-20 years), 10 cases Age (68 ± 4 .7) years old, group E (> 20 years), 10 cases, age (70 .8 ± 3 .6) years old. The levels of blood lipids, endocrine hormones and hemorheology in each group were measured. Results (1) With the increase of menopause, female blood lipids have an increasing trend. (2) The estrogen level of postmenopausal women gradually decreased with the increase of menopause, luteinizing hormone and follicle-stimulating hormone increased gradually and then decreased gradually. (3) Most of the hemorheology indexes of menopause women are in an abnormal state, in which the plasma viscosity increases with the increase of menopause age, and the change of erythrocyte sedimentation index and K value shows the first decrease and then gradually increase. Conclusions The duration of menopause in women determines the abnormalities of sex hormones, blood lipids and hemorheology in postmenopausal women. The longer the duration of menopause, the more significant the above indexes are abnormal