水、食品及药物中有几千种成分能够与亚硝酸盐反应而产生 N-亚硝基化合物。这种亚硝化反应的产物中,有几百种已做了致癌性动物实验,其中有一百多种已发现有致癌作用,有些甚至在很低剂量水平时就能致癌。当摄入亚硝酸盐和前致癌物(致癌的 N-亚硝基化合物的前体物)时,就可能在人的胃中形成致癌的 N-亚硝基化合物。这就引起了关 Thousands of ingredients in water, food and medicine react with nitrite to produce N-nitroso compounds. Of the products of this nitrosation reaction, hundreds have been tested for carcinogenicity in animals, of which more than 100 have been found to have carcinogenic effects, some of which can cause cancer even at very low dosage levels. When ingested nitrite and pro-carcinogens (precursors of oncogenic N-nitroso compounds), it is possible to form oncogenic N-nitroso compounds in the human stomach. This caused the closure