自 1999年 2月我们共收治老年神经外科病人 2 43例 ,其中有 9例应用甘露醇时发生急性肾功能衰竭 (ＡＲＦ) ,即甘露醇肾病 ,现报告如下。1　临床资料本组男 6例 ,女 3例 ;年龄 6 5～ 78岁 ,平均 6 8.5岁。入院治疗前 9例患者均无肾脏病史 ,肾功能检查Ｃｒ、ＢＵＮ均正常 ,其中合 Since February 1999 we have treated a total of 243 elderly neurosurgical patients, of which 9 cases of acute renal failure (ARF) when using mannitol, namely mannitol nephropathy, are as follows. 1 Clinical data The group of 6 males and 3 females; aged 6 5 to 78 years, mean 6 8.5 years old. Before admission, 9 patients had no history of renal disease, renal function tests Cr, BUN were normal, which combined