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肝纤维化是由于细胞外基质(ECM)的合成大于降解导致过度沉积,是纤维增生与纤维分解不平衡而引起的病理过程.是各种慢性肝病发展的必经阶段,由于多种致病因素引起肝脏的损伤和炎症所共有的病理特征,也是向肝硬化等进一步发展、恶化的重要中间环节.当今大量研究发现,肝纤维化是一个可逆的过程,早期诊断与及时给予有效治疗可减缓或防止发展成为肝硬化.现就肝纤维化的治疗研究现状作一简要综述.
Liver fibrosis is due to the extracellular matrix (ECM) synthesis than degradation caused by excessive deposition, is an imbalance of fiber proliferation and fibrosis caused by the pathological process is a necessary stage for the development of a variety of chronic liver disease due to a variety of risk factors Pathological features that cause liver damage and inflammation are also important intermediate links for the further development and worsening of cirrhosis, etc. A large number of researches have found that liver fibrosis is a reversible process, and early diagnosis and timely effective treatment can slow down or To prevent the development of cirrhosis is now a brief overview of the status of treatment of liver fibrosis.