论文部分内容阅读
目的分析研究坦索罗辛针对治疗晚期前列腺癌的治疗效果和安全性。方法对80例晚期前列腺癌患者资料进行回顾性分析,将80例患者随机分为观察组和对照组,每组40例,患者全部实施最大限度的雄激素阻断治疗方式,观察组患者在此基础之上使用坦索罗辛进行治疗,持续服用8周。结果在治疗4周以及8周后,观察组患者的生活质量评分、剩余尿量、最大尿流率、前列腺体积与对照组比较差异有统计学意义(P<0.05);两组患者的血压变化情况比较差异无统计学意义(P>0.05)。结论最大限度雄激素阻断治疗能够延长晚期前列腺癌患者的生存期,使用坦索罗辛能够有效改善患者的下尿路症状,增强患者的生活质量,患者出现不良反应的情况相对较低,值得在临床中加以推广使用。
Objective To analyze the effect and safety of tamsulosin in the treatment of advanced prostate cancer. Methods The data of 80 patients with advanced prostate cancer were retrospectively analyzed. Eighty patients were randomly divided into observation group and control group, with 40 patients in each group. All patients were treated with maximal androgen blockade therapy. Patients in observation group Based on the use of tamsulosin treatment, continuing to take 8 weeks. Results After 4 and 8 weeks of treatment, the quality of life scores, residual urine volume, maximum flow rate and prostate volume in the observation group were significantly different from those in the control group (P <0.05). The changes of blood pressure The difference was not statistically significant (P> 0.05). CONCLUSIONS: Maximal androgen blockade can prolong the survival of patients with advanced prostate cancer. Tamsulosin can effectively reduce the symptoms of lower urinary tract and improve the quality of life of patients. The incidence of adverse reactions in patients is relatively low, which is worth To promote the use of clinical.