一、概述蒽环类抗癌抗生素在肿瘤化疗中居重要地位。近年来,通过寻找产生这类抗生素的新变异株和结构改造的途径发现了许多新的同系物、衍生物,为肿瘤化疗提供了更多的药物。蒽环类抗癌药的基本结构如下。最早发现和生产蒽环类抗癌抗生素的意大利Farmitalia药厂的科学家认为, I. Overview Anthracycline anticancer antibiotics play an important role in cancer chemotherapy. In recent years, many new homologues and derivatives have been discovered by searching for new variants and structural transformations that produce such antibiotics, providing more drugs for cancer chemotherapy. The basic structure of anthracycline anticancer drugs is as follows. Scientists at Italy’s Farmitalia Pharmaceuticals, which first discovered and produced anthracycline anticancer antibiotics, believe that