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目的探讨胃上部癌和胃下部癌临床病理生物学的差异和淋巴结转移规律,揭示其临床意义。方法回顾性分析1997年1月至2007年1月间手术切除的32例胃上部癌与151例胃下部癌临床病理特点及淋巴结转移的规律。结果胃上部癌与胃下部癌在病灶直径、大体类型、分化程度、生长方式、浸润深度、病理分期、浆膜受侵等方面存在明显差异(P<0.05)并且有各自的淋巴结转移规律。结论胃上部癌表现出比较恶性的生物学行为。胃癌淋巴结转移的远近,与胃癌的浸润深度、大体类型、生长方式以及浆膜是否受侵有关。
Objective To investigate the clinicopathological differences and lymph node metastasis of upper gastric cancer and lower gastric cancer and to reveal its clinical significance. Methods The clinical and pathological characteristics of 32 cases of upper gastric cancer and 151 cases of lower gastric cancer surgically resected between January 1997 and January 2007 were analyzed retrospectively. Results There was a significant difference (P <0.05) in the diameter of gastric cancer, the general type, the degree of differentiation, the growth pattern, the depth of invasion, the pathological stage and serosal invasion of upper gastric cancer and lower gastric cancer, and had their own rules of lymph node metastasis. Conclusion Upper gastric cancer shows more malignant biological behavior. The extent of gastric cancer lymph node metastasis, and gastric cancer depth of invasion, the general type, growth pattern and whether the invasion of serosa.