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目的 检测脑囊虫病、病毒性脑膜脑炎及非神经系统疾病患者脑脊液内一氧化氮 (NO)含量变化 ,探讨NO参与人体对脑囊虫的免疫作用。方法 采用显色剂法检测实验组和对照组脑脊液NO含量 ,同时检测一般生化指标和细胞学指标。结果 脑囊虫病组脑脊液NO含量高于非神经系统疾病患者组 ,与病毒性脑膜脑炎患者无差异。结论 NO参与人体对囊虫的免疫过程 ,其作用长期存在 ,并可能通过某些作用影响中枢神经正常功能。
Objective To detect the content of nitric oxide (NO) in cerebrospinal fluid (CSF) in patients with cysticercosis, viral meningoencephalitis and non-neurological diseases, and to explore the role of nitric oxide (NO) in the human brain against cysticercosis. Methods The colorimetric method was used to detect the content of NO in cerebrospinal fluid of experimental group and control group. Meanwhile, the general biochemical and cytological indexes were measured. Results The cerebrospinal fluid NO content in cerebral cysticercosis group was higher than that in non-neurological disease group, there was no difference with viral meningoencephalitis patients. Conclusion NO participates in the immune process of the human body against cysticercosis and its role exists for a long time and may affect the normal function of the central nervous system through some actions.