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神经内分泌肿瘤(NEN)起源于胺前体摄取与脱羧酶细胞,胃肠道是NEN最常见的发病部位。其生物学特性、恶性程度、病理学特征及预后差异很大,多数患者缺乏典型临床表现。常用的治疗方法包括手术切除、化学治疗、放射治疗及内镜和介入治疗等。另外,一些新的靶向药物展现了良好的应用前景。目前,对于本病的治疗和预后,国内外学者尚缺乏统一认识。
Neuroendocrine tumors (NEN) originate from amine precursor uptake and decarboxylase cells, and the gastrointestinal tract is the most common site of NEN. The biological characteristics, malignancy, pathological features and prognosis vary greatly, the majority of patients lack the typical clinical manifestations. Common treatment methods include surgical resection, chemotherapy, radiation therapy and endoscopic and interventional therapy. In addition, some of the new targeted drugs have shown promising applications. At present, the treatment and prognosis of the disease, domestic and foreign scholars still lack of common understanding.