雷尼替丁(Ranitidine又名呋喃硝胺、善胃得),是继西咪替丁之后新开发的高效能的H_2受体拮抗剂,其分子结构中以一个呋喃环取代了原有的咪唑环,使其对壁细胞H_2受体的作用更强、更具有特异性。但随着临床上的广泛应用,其副作用也渐增多,并引起人们的关注,现将近年来国内外的有关文献综述如下,以供参考。一、一般不良反应及过敏反应:上海雷尼替丁协作组报道213例消化性溃疡患者口服雷尼替丁后, Ranitidine (Ranitidine aka nitrofurantoin, good stomach), is the newly developed cimetidine high-performance H 2 receptor antagonist, the molecular structure of a furan ring to replace the original imidazole Ring, making it more potent and more specific for parietal cell H 2 receptors. However, with the wide application in clinical practice, its side effects are gradually increasing and arousing people’s attention. In recent years, the relevant literature at home and abroad is summarized as follows for reference. First, the general adverse reactions and allergic reactions: Shanghai ranitidine collaborative group reported 213 cases of peptic ulcer patients after oral ranitidine,