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目的:对比分析保留和去除上皮瓣的LASEK矫治近视的临床疗效。方法:263例(526眼)近视患者进行对照分析,术中随机分为去瓣组(Ⅰ组)和留瓣组(Ⅱ组),对比分析2组术后裸眼视力、最佳矫正视力、角膜上皮愈合时间、角膜上皮下雾状混浊(haze)程度以及眼部刺激症状。结果:术后3个月,留瓣组3个月达术前最佳矫正视力245眼(占93.2%),而去瓣组为238眼(占90.5%),两组差异无统计学意义(P>0.05),2组均无最佳矫正视力下降大于1行者。去瓣组术后3d角膜上皮愈复率达73.05%,而留瓣组仅16.67%,两组差异有统计学意义(P<0.05)。去瓣组角膜上皮平均愈复时间较留瓣组明显缩短。两组患者术后角膜上皮下混浊的发生无统计学差异(P>0.05)。结论:去除上皮瓣不影响LASEK的疗效,并且能减轻患者的眼部刺激症状,缩短上皮愈合时间。
Objective: To compare and analyze the clinical effect of preserving and removing epithelial flap LASEK in the treatment of myopia. Methods: A total of 263 eyes (526 eyes) with myopia were randomly divided into two groups: flap-free group (group Ⅰ) and left flap group (group Ⅱ). The postoperative uncorrected visual acuity, Epithelial healing time, degree of corneal haze, and ocular irritation. Results: At 3 months after operation, the best corrected visual acuity was 93 eyes (93.2%) in 3 months and 238 eyes (90.5%) in the flapless group, with no significant difference between the two groups P> 0.05). There was no best corrected visual acuity drop of more than 1 in both groups. The healing rate of corneal epithelium in postoperative flap group was 73.05%, while that in left flap group was only 16.67%. There was significant difference between the two groups (P <0.05). The average recovery time of corneal epithelium in flap group was shorter than that in left flap group. There was no significant difference in the occurrence of corneal epithelial opacification between the two groups (P> 0.05). Conclusion: The removal of epithelial flap does not affect the efficacy of LASEK, and can alleviate the symptoms of eye irritation and shorten the healing time of epithelial cells.