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目的:探讨心先安对急性心肌梗死(AMI)的抗缺血作用。方法:62例AMI患者于发病后10日随机分为心先安组(n=30):在常规治疗AMI的基础上加用心先安90mg静滴,每日2次,连续10日;对照组(n=32):给予常规AMI治疗。两组患者定时作心电图和血清肌酸激酶(CK)和血清肌酸激酶同工酶(CK-MB)检查。结果:心先安组血清心肌酶高峰前移,心电图中心肌缺血的范围和程度较对照组明显缩小(P<0.05)。结论:心先安可以缩小AMI患者的心肌梗死面积,改善心肌缺血。
Objective: To investigate the anti-ischemic effect of Xin Xian on acute myocardial infarction (AMI). Methods: Sixty-two patients with AMI were randomly assigned to receive Xinxianan (n = 30) on the 10th day after the onset of symptoms. On the basis of conventional AMI, intravenous infusion of 90mg of propranolol was administered twice daily for 10 days. (n = 32): given conventional AMI treatment. Two groups of patients with regular ECG and serum creatine kinase (CK) and serum creatine kinase (CK-MB) examination. Results: The level of serum myocardial enzyme and the degree of myocardial ischemia in ECG decreased significantly compared with those in control group (P <0.05). Conclusion: Xian Xian can reduce myocardial infarction AMI area, improve myocardial ischemia.