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【目的】探讨妊娠期糖尿病(GDM)空腹血糖(FBG)的特点和对妊娠结局的影响。【方法】采用回顾性研究的方法,选择2006年1月至2007年6月在我院进行常规产前检查和住院分娩确诊为GDM的孕妇182例,根据75g糖耐量试验(OGTT)中FBG或FBG分为FBG正常组(A组)114例和FBG升高组(B组)68例进行临床资料分析。【结果】①FBG与GCT及OGTT各时点血糖呈正相关。GCT1h血糖≥11.1mmol/L的GDM中FBG≥5.8mmol/L占71.1%。②两组孕产妇并发症比较差异无显著性(P>0.05)。但FBG升高的GDM孕妇需胰岛素治疗发生率(19.1%)明显高于FBG正常组(5.3%),两组差异有显著性(P<0.05)。③FBG升高组新生儿出生体重高于FBG正常组,巨大儿、新生儿窒息、新生儿高胆红素血症发病率明显增加。【结论】①GCT1h血糖≥11.1mmol/L时,应先行FBG检查确诊是否为GDM。②FBG升高的GDM围产儿危险性增加,必须加强监测。
【Objective】 To investigate the characteristics of fasting blood glucose (FBG) in gestational diabetes mellitus (GDM) and its effect on pregnancy outcome. 【Methods】 A retrospective study was conducted to select 182 pregnant women who were diagnosed as GDM by routine prenatal examination and hospital delivery in our hospital from January 2006 to June 2007. According to the results of 75g glucose tolerance test (OGTT), FBG or FBG was divided into FBG normal group (A group) 114 cases and FBG elevated group (B group) 68 cases of clinical data analysis. 【Results】 ①FGG was positively correlated with GCT and OGTT at all time points. FBG≥5.8mmol / L accounted for 71.1% of GDM in GCT1h blood glucose≥11.1mmol / L. ② There was no significant difference in the complications between the two groups (P> 0.05). However, the incidence of insulin therapy in GDM pregnant women with FBG (19.1%) was significantly higher than that in FBG normal group (5.3%), the difference was significant (P <0.05). (3) The birth weight of newborn infants with FBG elevated group was higher than that of FBG normal group. The incidence of neonatal hyperbilirubinemia was significantly increased in giant infants and neonates with asphyxia. 【Conclusion】 ①GCT1h blood glucose ≥11.1mmol / L, FBG should be the first diagnosis of whether the diagnosis of GDM. ② FBG increased risk of perinatal GDM increased, we must strengthen the monitoring.