论文部分内容阅读
近年来在国内外癌胚抗原(carcinoembryonic antigen,CEA)已被广泛应用于消化道肿瘤及其他部位恶性肿瘤的诊断与手术后的追踪。1965年Gold等首次发现胎儿组织和人类结肠腺癌组织中存在CEA,其后研究发现CEA亦存在于其他部位上皮衍生的肿瘤组织中,并证明正常成人大肠和循环中亦有少量CEA存在。CEA是一种糖蛋白,其分子量为150,000～200,000doltons。近年来对提纯的CEA抗原的生理化学性质的研究有了进一步发展,发现不同部位的CEA中,碳水化合物含量不一,胃肠道CEA碳水化合物含量为
In recent years, carcinoembryonic antigen (CEA) at home and abroad has been widely used in the diagnosis and tracking of malignant tumors of digestive tract tumors and other sites. In 1965, Gold et al. first discovered the presence of CEA in fetal tissue and human colon adenocarcinoma. Later, it was found that CEA was also present in epithelial-derived tumor tissues at other sites, and that there was also a small amount of CEA in the normal adult large intestine and circulation. CEA is a glycoprotein with a molecular weight of 150,000 to 200,000 doltons. In recent years, further studies have been carried out on the physiochemical properties of purified CEA antigens. It has been found that CEA in different parts has different carbohydrate content and CEA carbohydrate content in the gastrointestinal tract is