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目的:探讨液基薄层细胞(TCT)法与宫颈刮片法在检测宫颈病变的优劣性。方法:选择2011年6月~2012年12月甘肃省金昌市金川集团公司接受体检的女工2 450例,研究不同方法检测宫颈病变尤其是细胞学检查的优劣性,以病理检查结果作为评价标准。结果:TCT组宫颈病变检出率为20.74%,宫颈刮片组为1.41%;TCT组炎症检出率为36.79%、宫颈刮片组为0;TCT组癌前病变检出率为95.56%、宫颈刮片组为78.26%;TCT组与活检及复查结果的符合率为62.79%,宫颈刮片组为50.00%;TCT组标本满意度为100.00%,宫颈刮片组为40.00%。以上指标2种方法比较差异有统计学意义(P<0.05)。结论:与传统宫颈刮片相比,TCT检测技术明显提高了标本的满意度及宫颈病变的检出率,减少了漏诊率,与宫颈活检的符合率高,在临床病理诊断中具有良好的应用前景。
Objective: To investigate the advantages and disadvantages of liquid-based thin-layer cell (TCT) and cervical smears in the detection of cervical lesions. Methods: From June 2011 to December 2012, 2,450 female workers in Jinchuan Group Company of Jinchang City, Gansu Province were selected to study the advantages and disadvantages of different methods to detect cervical lesions, especially cytology. The results of pathological examination were used as evaluation criteria . Results: The detection rate of cervical lesions in TCT group was 20.74%, in cervical smear group was 1.41%, in TCT group was 36.79%, in cervical smear group was 0. The detection rate of TCT group was 95.56% The cervical smear group was 78.26%. The coincidence rate of TCT group with biopsy and reexamination results was 62.79% and that of cervical smear group was 50.00%. The satisfaction of TCT group was 100.00% and that of cervical smear group was 40.00%. There are significant differences between the above two methods (P <0.05). Conclusion: Compared with the traditional cervical smear, TCT detection technology significantly improves the satisfaction of specimens and the detection rate of cervical lesions, reducing the rate of misdiagnosis, consistent with the high rate of cervical biopsy, has a good clinical and pathological diagnosis prospect.