Synthesis of Novel Isoxazole-contained Analogues of Losartan

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：jiangfan520

【摘要】

：

A series of novel isoxazole-contained analogues of Losartan were designed and synthesized with 1,3-DC reaction. The regioselectivity of the reaction was discuss

【作者】

：

Jian Wu WANG Jiong JIA Hong Me

【机构】

：

School of Chemistry and Environmental Science

【出处】

：

中国化学快报（英文版）

【发表日期】

：

2004年期

【关键词】

：

analogues of losartan Synthesis 1 3-DC antihyertensin

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A series of novel isoxazole-contained analogues of Losartan were designed and synthesized with 1,3-DC reaction. The regioselectivity of the reaction was discussed and the compounds are potential antihypertensive.

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Synthesis of Novel Isoxazole-contained Analogues of Losartan

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