慢性粒细胞白血病(以下简称慢粒)在小儿中较少见,最终常死于急粒变,而有关小儿慢粒急淋变的报告甚少。我科曾收治2例,其中1例进行了超微结构观察,现报告如下。例1男,13岁,汉族。因面色苍白、乏力10个月,加重伴发热20天,于1988年3月6日入院。起病时曾住我院二附院。当时血象:血红蛋白65g/L;白细胞294×109/L,原粒0.01,早幼粒0.05,中幼粒0.17,晚幼粒0.20,杆状核0.21,分叶核0.28;血小板375×10~9/L。骨髓象:有核细胞增生极度活跃,粒:红=64:1,原粒0.025,早幼粒0.06,中、晚幼粒各0.20.杆状核0.185,分叶核0.17,嗜酸中幼粒0.025,嗜酸晚幼粒0.07,嗜碱粒细胞0.025。确诊为 Chronic myelogenous leukemia (hereinafter referred to as chronic granulocyte) is rare in children, and often dies of sudden granuloma. However, reports of chronic granulocyte leukemia in children are rarely reported. Our department has been treated in 2 cases, of which 1 case has been observed for ultrastructure. The report is as follows. Example 1 Male, 13 years old, Han ethnicity. He was admitted to hospital on March 6, 1988 because he was pale and weak for 10 months, he was aggravated with fever for 20 days. I lived in the Second Affiliated Hospital of our hospital when I became ill. At the time of hemogram: hemoglobin 65g/L; white blood cells 294×109/L, raw particles 0.01, promyeloplasm 0.05, middle and young particles 0.17, late young particles 0.20, rod-shaped nucleus 0.21, lobular nucleus 0.28; platelet 375×10~9 /L. Bone marrow image: hypertrophy of nucleated cells is extremely active, Granules: Red = 64:1, Granules 0.025, Granules 0.06 for early progess, Middle and late granules 0.20 each, Rod-like nucleus 0.185, Segmented nucleus 0.17, Eosinophilic granules 0.025, eosinophilic late grain 0.07, basophils 0.025. Diagnosed as