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木糖醇注射液,早在60年代国外就试用于治疗糖尿病,日本药局方第九、第十改正版已相继收载。近年来,国内的几个厂家先后生产应用。木糖醇的含量测定,四川省和北京市药品标准均采用碘量法,由于不能适应配制过程中质量监测快速分析的需要,本文试验用折光法测定木糖醇注射液的含量,并与碘量法作了比较,方法简便,结果满意,现报道如下:一、仪器、样品与试剂1.阿贝折光计(WZS-1型),上海光学仪器厂.
Xylitol injection, as early as 60 years abroad to try to treat diabetes, the Japanese Pharmacopoeia ninth, tenth revised version has been included. In recent years, several domestic manufacturers have production applications. Xylitol content determination, Sichuan Province and Beijing City drug standards are used iodometric method, due to the preparation process can not meet the needs of rapid monitoring of quality monitoring, xylitol injection test using refractive index content, and iodine Quantitative method for comparison, the method is simple, the results are satisfactory, are reported as follows: First, instruments, samples and reagents 1. Abbe refractometer (WZS-1 type), Shanghai Optical Instrument Factory.