随着高脂血症发病率的增加，高三酰甘油血症性急性胰腺炎（ HTG－AP）的发生率也明显增加，它已成为继胆石疾病和酒精之后引发急性胰腺炎的第三大病因。严重的 HTG 可加剧胰腺炎的病情，并增加胰腺炎的发病率和病死率。 HTG－AP明确的致病机制至今仍不清楚，其临床特点与其他病因引起的急性胰腺炎相似，但又具有特殊性。目前，采用饮食干预、药物治疗（降脂药物、胰岛素、低分子肝素）、血液净化等综合性措施治疗HTG－AP。“,”Due to the increase in the incidence of hyperlipidemia ,the incidence of hypertriglyceridemia-induced acute pancreatitis (HTG-AP) significantly increases as well,and hypertriglyceridemia has become the third major common cause of pancreatitis after alcohol and gall stone disease .Severe HTG pancreatitis may exacerbate the condition of pancreatitis and increase the morbidity and mortality .The exact pathophysio-logical mechanism of HTG-AP still remains unclear.The clinical presentation of HTG-AP is generally no dif-ferent from AP of any other etiology, yet some specific clinical characteristics of HTG-AP are observed.To date,comprehensive therapy including dietary modification ,pharmacotherapy ( lipid-lowering drugs,insulin, low molecular weight heparin) and blood purification are used in treating HTG-AP.