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目的:针对临床骨肿瘤微波热疗模型,对不同结构的微波热疗探头在骨组织中产生的电磁场分布及单位质量电磁能量吸收率(SAR)进行模拟计算。方法:采用有限元数值分析方法,治疗模型为圆柱型分层骨肿瘤组织,对两种不同结构的插入探头进行数值,一种是目前在唐都医院骨肿瘤微波热疗中临床使用的简单同轴探头,采用同轴线玻掉外导体构成,另一种为微波插入热疗中广泛使用的同轴缝隙探头。结果:数值模拟结果显示:目前临床使用的简单同轴探头产生的电磁能量主要分布在治疗区域外,且在治疗组织中分布很不均;缝隙探头则能较好地把能量传输到组织内部,能量主要集中在探头缝隙附近,可通过调整缝隙位置方便地调整控制治疗部位;对离体牛腿骨的实验结果与模拟的结果相吻合。结论:简单同轴探头的计算结果与临床治疗中存在的治疗效率低、治疗时间长、组织加热严重不均等问题相吻合。该模拟结果将为微波骨肿瘤临床治疗的改进提供理论依据。
OBJECTIVE: To simulate the electromagnetic field distribution and the mass energy absorption of electromagnetic energy (SAR) produced by bone tissue of microwave hyperthermia probes with different structures based on the microwave hyperthermia model of clinical bone tumors. Methods: Finite element method was used to treat the tumor. The treatment model was cylindrical layered tumor tissue, and the values of two different types of probe were calculated. One is the clinical application of microwave hyperthermia in Tangdu Hospital Axis probe, the outer conductor with a coaxial cable Bose composition, and the other for the microwave insertion thermocouple coaxial probe widely used. Results: The numerical simulation results show that the electromagnetic energy generated by the simple coaxial probe used in clinical practice is mainly distributed outside the treatment area and distributed unevenly in the treated tissue. The slit probe can transmit the energy to the tissue well, The energy is mainly concentrated near the probe gap, and the position of the controllable treatment can be easily adjusted by adjusting the position of the gap. The experimental results of the isolated cow bone coincide with the simulation results. Conclusion: The calculation results of simple coaxial probe coincide with the problems of low therapeutic efficiency, long treatment time and severe heating of tissue in clinical treatment. The simulation results will provide a theoretical basis for the improvement of clinical treatment of microwave bone tumors.