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炎症性肠病(IBD)包括溃疡性结肠炎(UC)和克罗恩病(CD),近年来发病率呈上升趋势。虽然发病机制尚不明确,但已知肠道黏膜免疫系统异常是该病发病的重要因素,微生物感染因素在其发生和发展中亦起着一定作用。虽然尚未找到某一特异微生物病原感染与IBD有恒定关系,但IBD患者由于本身免疫功能紊乱,较正常人更容易感染具备肠道侵袭性的机会致病病毒和细菌,而感染后IBD的病情会进一步加重形成
Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn’s disease (CD), and the incidence has been on the rise in recent years. Although the pathogenesis is not clear, but known intestinal mucosal immune system abnormalities is an important factor in the pathogenesis of microbial infection factors in its occurrence and development also play a role. Although a specific microbial pathogen infection has not yet been found to have a constant relationship with IBD, IBD patients are more susceptible to opportunistic pathogenic viruses and bacteria that enter the gut due to their own immune dysfunction than normal people, and the IBD condition after infection Further increase the formation