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目的:观察消瘀散醇提物电离子导入对深静脉血栓形成(DVT)的临床效果及CD62-P的影响,探讨其作用机理.方法:将60例DVT患者分为治疗组、对照组,每组30例.治疗前及治疗后第3、7、10天进行VAS疼痛、肿胀、CD62-P表达检查,以及疗效评定.结果:治疗后3d、7d、10d,两组疼痛、CD62-P表达量比较,差异均有统计学意义(P＜0.05);治疗后3d、7d,两组肿胀比较,差异均有统计学意义(P＜0.05),其中治疗后10d两组比较,差异无统计学意义(P>0.05),对照组组内在治疗后7d、10d比较,差异有统计学意义(P＜0.01);两组治疗10d后,治疗组有效率为83.3％,对照组为76.7％,两组疗效差异有统计学意义(P＜0.05).结论:消瘀散醇提物电离子导入治疗DVT效果良好,可能与降低CD62-P表达量有关.“,”Objective:To observe the effect of deep venous thrombosis (DVT) in alcohol txtrac of Xiaoyu powder by iontophoresis and the effect on the expression of CD62-P.Methods:The 60 patients with DVT were divided into treatment group and control group,30 cases in each group.The VAS,swelling and the expression of CD62-P were detected before treatment and after the treatment of 3d,7d and 10d,and the curative effect was evaluated.Results:After the treatment of 3d,7d and 10 d,VAS pain and CD62-P expression between two groups were statistically significant (P＜0.05);In swelling,the difference was statistically significant (P＜0.05)between the two groups after the treatment of 3 d and 7 d,but the difference was not statistically significant (P＞0.05) after the treatment of 10d.The difference on swelling scores between 7d and 10d after treatment,was statistically significant in control group (P＜0.01).The effective rate was 83.3％ in treatment group and 76.7％ in the control group,and the difference efficacy was statistically significant (P＜0.05) between the two groups.Conclusion:Alcohol extract of Xiaoyu powder by iontophoresis showed remarkable effect on DVT and it may be related to the decrease of expression of CD62-P.