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目的:分析糖皮质激素类药物应用情况,分析用药误区,提供提出药学干预对策。方法:利用医院计算机病例系统,调取2011年1月~2014年12月相关处方,进行回顾性分析以及合理用药评价。结果:门诊处方中占比前2位皮肤科、耳鼻喉科,频数前4位地塞米松冻干粉(5mg)、卤米松三氯生乳膏、曲安奈德益康唑乳膏、强的松片;住院处方DDc排序前五位甲泼尼龙针(0.5g)、氢化泼尼松针(10mg/2ml)、复方倍他米松针(1ml)、甲泼尼龙针(40mg)、氢化可的松琥珀酸钠针(50mg);500份住院处方患者年龄5个月~85岁,危重症80.4%,主要用于止吐、抗炎、抗过敏、免疫抑制、联合化疗,联合其他药物37.6%;不合理用药12.8%。结论:糖皮质激素类药物用药水平亟待改进,需加强主要科室用药管理,加强药学干预、规范意识用药行为、加强对患者宣传。
OBJECTIVE: To analyze the application of glucocorticoid drugs, analyze the misunderstandings of drug use and provide countermeasures for the intervention of pharmacy. Methods: Using the hospital computer case system, the relevant prescriptions from January 2011 to December 2014 were retrieved and analyzed retrospectively and the evaluation of rational drug use. Results: Outpatient prescriptions accounted for the first two dermatology, otolaryngology, frequency of the first four dexamethasone lyophilized powder (5mg), halometuron triclosan cream, triamcinolone acetonide cream, prednisone The top 5 inpatients prescribed methylprednisolone (0.5 g), prednisone (10 mg / 2 ml), betamethasone (1 ml), methylprednisolone (40 mg), hydrocortisone amber Acupuncture (50mg); 500 hospitalized patients aged 5 months to 85 years old, 80.4% critically ill, mainly for antiemetic, anti-inflammatory, anti-allergic, immunosuppressive, combined with chemotherapy, combined with other drugs 37.6%; Rational use of medicine 12.8%. Conclusion: The medication level of glucocorticoids need to be improved urgently. It is necessary to strengthen the administration of medication in major departments, strengthen the pharmaceutical intervention, standardize the behavior of consciousness medication and strengthen the publicity to patients.