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目的探讨老年前列腺增生患者血清PSA、IPSS症状评分和前列腺体积与勃起功能障碍之间的关系。方法应用IIEF-5国际勃起功能指数问卷表对入选的BPH患者进行阴茎勃起功能障碍评估,以13分为临床诊断分界线,分为A组(≤12分的为性功能较差的BPH组)和B组(≥13分的为性功能较好的BPH组);两组病例均分别进行IPSS评分、经直肠B超前列腺体积和血清PSA值测定。结果本研究共收集病例108例,年龄59～89岁,平均年龄(73.67±5.41),BPH伴发ED的发生率为49.07%。A、B两组之间IPSS评分值分别为(23.23±6.05)、(19.98±7.16),两组比较,差异有统计学意义P<0.05,同时对两组IPSS评分和IIEF评分之间行相关分析得出r=0.115,有一定的相关性。A、B两组前列腺体积测定值分别为(63.19±35.38)ml、(58.91±34.99)ml,两组比较差异无统计学意义(P>0.05)。A、B两组PSA值分别为(5.25±4.48)ng/d1、(4.48±4.46)ng/dl,两组比较差异无统计学意义(P>0.05);同时对IPSS评分与IIEF-5评分行相关分析,r=0.24,显示一定的相关性。结论 BPH患者有很高的ED发生率。血清PSA与前列腺体积测定值和IPSS评分值有明显的相关性,下尿路症状明显的患者ED发生的风险率更高。
Objective To investigate the relationship between serum PSA, IPSS symptom score, prostate volume and erectile dysfunction in elderly patients with benign prostatic hyperplasia. Methods The IIEF-5 International Index of Erectile Function Inventory was used to evaluate erectile dysfunction in selected BPH patients. The clinical diagnostic criteria were divided into three groups: group A (≤12 for poor sexual function BPH group) And group B (≥13 points for better sexual function BPH group); IPSS score, transrectal B-prostate volume and serum PSA were measured in both groups. Results A total of 108 cases were collected in this study, ranging in age from 59 to 89 years with a mean age of 73.67 ± 5.41. The incidence of ED with BPH was 49.07%. The scores of IPSS in group A and group B were (23.23 ± 6.05) and (19.98 ± 7.16) respectively, there was a significant difference between the two groups (P <0.05). The correlation between IPSS score and IIEF score Analysis found that r = 0.115, a certain correlation. The measured values of prostate volume in groups A and B were (63.19 ± 35.38) ml and (58.91 ± 34.99) ml, respectively. There was no significant difference between the two groups (P> 0.05). The PSA values of A, B were (5.25 ± 4.48) ng / d1, (4.48 ± 4.46) ng / dl respectively, there was no significant difference between the two groups (P> 0.05) Line-related analysis, r = 0.24, showing a certain degree of correlation. Conclusion BPH patients have a high incidence of ED. There was a clear correlation between serum PSA and prostate volume and IPSS scores, and patients with obvious symptoms of lower urinary tract had a higher risk of developing ED.