论文部分内容阅读
儿童肾病综合征(NS)90％以上对类固醇治疗敏感,但其中有80％以上病例在最终痊愈之前有一次或多次复发。既往发表的关于NS的随访资料只限于儿童期并未延长到成年。本文对150例于1951～1967年间确诊为NS的患者情况进行了随访调查。他们起病时的年龄为11个月至14岁(平均3.6岁),男女之比为1.9:1。全部病例按症状分为2组。A组或低危组为“单纯性”肾病,其特点为:年龄>1岁和<8岁,镜下血尿RBC不超过5个/HP,血压正常[舒张压<90mmHg(12Kpa)],如做了肾活检则符合微小病变型的组织学特征,临床表现典型,对激素治疗敏感;B组有以下一项或多项特证:年龄<1岁或>8岁,镜下血尿RBC>5个/HP,脓尿之尿之中白细胞 5个/
More than 90% of children with nephrotic syndrome (NS) are susceptible to steroid therapy, but more than 80% of these cases have one or more recurrences before they finally heal. Previously published data on NS follow-up were limited to adulthood not extended to childhood. In this paper, 150 cases of patients diagnosed with NS between 1951 and 1967 were followed up. Their age at onset was 11 months to 14 years (mean 3.6 years), with a ratio of men to women of 1.9: 1. All cases were divided into 2 groups according to symptoms. A group or low-risk group as “simple” nephropathy, characterized by: age> 1 year and <8 years, microscopic hematuria RBC does not exceed 5 / HP, normotension [diastolic blood pressure <90mmHg (12Kpa)], such as Renal biopsy is consistent with the histological features of minimal lesions, the typical clinical manifestations of hormone therapy is sensitive; B group has one or more of the following special features: age <1 year or> 8 years, microscopic hematuria RBC> 5 A / HP, white blood in pyuria 5 /