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目的:评价派丽奥软膏辅助治疗慢性牙周炎的疗效。方法:40例慢性牙周炎病例按就诊顺序随机分组,在牙周洁刮治疗基础上,以碘甘油辅助治疗为对照组,记录实验组和对照组在基线、用药后各时间点的临床指标PLI、SBI、PD、AL,并进行统计学处理。结果:实验组在用药后6个月内的PLI与对照组或基线比较均显著降低(P<0.05),但用药后9个月和12个月均无显著差异(P>0.05);实验组在用药后1～12个月的SBI、PD和AL与对照组或基线比较均显著降低(P<0.05),用药后12个月的SBI除外)。结论:在单疗程治疗后6个月内,派丽奥软膏辅助治疗慢性牙周炎的各项检测指标的改善均优于碘甘油。
OBJECTIVE: To evaluate the efficacy of Pailin ointment in the treatment of chronic periodontitis. Methods: Forty patients with chronic periodontitis were randomized according to the order of treatment. On the basis of periodontal cleaning, iodine-glycerol adjuvant therapy was used as the control group. Clinical parameters of the experimental group and the control group at baseline and after administration were recorded PLI, SBI, PD, AL, and statistical analysis. Results: Compared with control group or baseline, PLI in experimental group decreased significantly (P <0.05) within 6 months after treatment, but no significant difference was found between 9 and 12 months after treatment (P> 0.05) The SBI, PD, and AL were significantly decreased (P <0.05) at 1 to 12 months after treatment compared with the control group or baseline except for SBI at 12 months after treatment. Conclusion: Within 6 months after the single course of treatment, the improvement of the detection indexes of Paillio ointment in the treatment of chronic periodontitis is better than that of iodine glycerol.