论文部分内容阅读
目的探讨影响2型糖尿病(T2DM)患者糖尿病足(DF)发生的相关危险因素。方法将276例诊断为T2DM的患者按有无糖尿病足分为糖尿病组和糖尿病足组,搜集并记录所有患者的临床资料及实验室指标,比较两组在各临床危险因素之间的差异。结果2组年龄、病程、SBP、DBP、2 h PG、HbA1C、HDL-C、LDL-C、Fbg、Scr、BUN、总蛋白、白蛋白、糖尿病肾病等因素差异有统计学意义(P<0.05);多因素非条件Logistic回归分析显示,糖尿病病程、HbA1c、Fbg、白蛋白及糖尿病肾病5个因素进入回归模型,是2型糖尿病患者发生糖尿病足的独立危险因素。结论严格控制血糖、血黏度,积极治疗各种DM并发症能有效预防DF发生。
Objective To investigate the related risk factors of diabetic foot (DF) affecting type 2 diabetes mellitus (T2DM). Methods 276 patients diagnosed as T2DM were divided into diabetic group and diabetic foot group according to whether they had diabetes mellitus, the clinical data and laboratory indexes of all patients were collected and recorded, and the differences between the two groups in clinical risk factors were compared. Results There were significant differences in the age, course of disease, SBP, DBP, 2 h PG, HbA1C, HDL-C, LDL-C, Fbg, Scr, BUN, total protein, albumin and diabetic nephropathy ). Multivariate non-conditional logistic regression analysis showed that diabetes duration, HbA1c, Fbg, albumin and diabetic nephropathy entered the regression model, which was an independent risk factor for type 2 diabetic patients. Conclusion Strict control of blood glucose, blood viscosity, active treatment of various DM complications can effectively prevent the occurrence of DF.