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头孢菌素类抗生素的HPLC测定法的研究丁丽霞,于如嘏,倪坤仪等。中国医药工业杂志,1993,24(10):465将色谱优化过程分为4步:(1)应用不完全因子设计从多个影响保留时间的因素中选择两个主要因素作为待优化的参数,经8个实验确定以RP-HPLC...
Study on HPLC Determination of Cephalosporin Antibiotics Ding Lixia, Yu Ruyi, Ni Kunyi et al. Chinese Journal of Pharmaceutical Industry, 1993,24 (10): 465 The chromatographic optimization process is divided into four steps: (1) the application of incomplete factorial design from a number of factors that affect the retention time of the two main factors to be selected as the parameters to be optimized, After eight experiments to determine RP-HPLC ...