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目的观察乳腺癌保留乳房手术应用术中放射治疗后近期疗效、安全性及美容效果等。方法对64例乳腺癌患者行保留乳房手术治疗,并于术中给予放射治疗。观察术后近期疗效、安全性及美容效果等。结果术后随访3~19个月,中位随访10.3个月。64例患者中,1例(1.6%)于1年后局部复发;7例(10.9%)术后发生Ⅰ级放射性肺损伤,10例(15.6%)手术部位局部硬化,8例(12.5%)皮肤颜色改变,8例(12.5%)手术部位疼痛;美容效果方面,达到极好或较好水平共占95.3%(61/64)。结论术中放射治疗在乳腺癌保留乳房手术中的应用可得到满意的近期疗效,且具有较高的临床安全性,同时美容效果良好。
Objective To observe the short-term curative effect, safety and cosmetic effect of intraoperative breast irradiation after breast cancer surgery. Methods Sixty-four patients with breast cancer underwent conservative breast surgery and received radiotherapy during the operation. To observe the short-term postoperative efficacy, safety and cosmetic effects. Results The patients were followed up for 3 to 19 months, with a median follow-up of 10.3 months. Of the 64 patients, 1 (1.6%) had local recurrence one year later; 7 (10.9%) had grade I radiation-induced lung injury, 10 (15.6%) had local sclerosis and 8 (12.5% Skin color change, 8 cases (12.5%) of the surgical site pain; beauty effect, to achieve a good or better level accounted for a total of 95.3% (61/64). Conclusion The application of intraoperative radiotherapy in breast conserving breast surgery can be satisfied with the short-term efficacy, and has high clinical safety, while the cosmetic effect is good.