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以可变误差多面体法处理多波长吸光光度数据同时测定了复方新诺明制剂模拟样和五个批号实际样品中磺胺甲恶唑(SMZ)、甲氧苄氨嘧啶(TMP)的含量,11 份模拟样中SMZ、TMP的回收率分别为99.8% 和100.3% ,复方新诺明片和注射液的测定结果与药典方法一致。
The multi-wavelength absorbance data were processed by the variable error polyhedron method. Simultaneous determination of sulfamethoxazole (SMZ) and trimethoprim (TMP) in the simulacrums of Simvastatin and the actual samples of five batches, 11 The recoveries of SMZ and TMP in the simulated samples were 99.8% and 100.3%, respectively. The results of the determination of cotrimoxazole and injection were consistent with those of the pharmacopoeia.