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目的探讨骨髓移植病人造血功能恢复的敏感指标。方法利用全自动血细胞分析仪测定21例骨髓移植病人网织红细胞(RET)、未成熟网织红细胞组分(IRF)、高散射光网织红细胞(HLR)、白细胞(WBC)、中性粒细胞绝对计数(ANC)、血小板(PLT),并进行对比分析。结果移植后骨髓造血功能恢复的天数(中位数)分别为:RET为16天,IRF为9.5天,HLR为9.5天,WBC为17天,ANC为11天,PLT为22.5天。结论IRF和HLR是较敏感的指标,结合ANC一起作为病人移植后骨髓造血功能恢复的指标有较大临床应用价值。
Objective To investigate the sensitive index of hematopoietic recovery in patients with bone marrow transplantation. Methods Twenty-one patients with bone marrow transplantation were enrolled in this study. RET, immature reticulocyte fraction (IRF), high-rewet reticulocyte (HLR), white blood cell (WBC), neutrophil Absolute count (ANC), platelet (PLT), and comparative analysis. Results The median number of days (median) for bone marrow hematopoietic function recovery after transplantation was RET 16 days, IRF 9.5 days, HLR 9.5 days, WBC 17 days, ANC 11 days and PLT 22.5 days. Conclusions IRF and HLR are more sensitive indicators. Combined with ANC, it has great clinical value as an index of recovery of hematopoietic function of bone marrow after transplantation.