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目的 :探讨肾病综合征外周微循环白色微血栓形成时PLT、MPV、PDW、PCT四项参数的变化。方法 :正常对照组 10 0人 ,肾病综合征无白色微血栓组 (Ⅰ组 ) 71人 ,肾病综合征合并白色微血栓组 (Ⅱ组 ) 2 9人。用CoulterJT -IR型血液分析仪检测PLT、MPV、PDW、PCT。结果 :Ⅱ组PLT、MPV、PDW、PCT均较对照组明显增加。Ⅰ组PLT、PDW、PCT较对照组明显增加 ,MPV明显减小。Ⅱ组PLT较Ⅰ组明显减少 ,MPV、PDW明显增加。结论 :肾病综合征合并白色微血栓时 ,PLT增加 ,MPV增大。血小板处于高度活化状态
Objective: To investigate the changes of four parameters of PLT, MPV, PDW and PCT in the peripheral microcirculation micro-thrombosis of nephrotic syndrome. Methods: There were 10 normal controls, 71 patients with nephrotic syndrome without white microthrombosis (group Ⅰ), and 29 with nephrotic syndrome and white microthrombi (group Ⅱ). PLT, MPV, PDW, PCT were detected with a Coulter JT-IR hematology analyzer. Results: The PLT, MPV, PDW and PCT in group Ⅱ were significantly higher than those in control group. Group Ⅰ PLT, PDW, PCT significantly increased compared with the control group, MPV was significantly reduced. Group Ⅱ PLT significantly decreased compared with the group, MPV, PDW increased significantly. Conclusion: Nephrotic syndrome combined with micro-thrombosis, PLT increased, MPV increased. Platelets are highly activated